Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL8307756 | 0.84 | ALDH1A1 (0.34) | ALDH1A1LMNA | |
| SCHEMBL15694063 | 0.79 | DGKA (0.39) | ALDH1A1LMNA | |
| SCHEMBL2533392 | 0.77 | LMNA (0.33) | ALDH1A1LMNA | |
| Chloroform SCHEMBL8311138 | 0.76 | PRKCA (0.40) | — | |
| SCHEMBL11058319 | 0.74 | LMNA (0.34) | ALDH1A1LMNA | |
| SCHEMBL2528605 | 0.74 | NAAA (0.38) | ALDH1A1LMNA | |
| SCHEMBL2795301 | 0.73 | ADRA2A (0.32) | — | |
| SCHEMBL1149297 | 0.73 | — | — | |
| SCHEMBL5011564 | 0.73 | RAB9A (0.44) | ALDH1A1LMNA | |
| SCHEMBL29021423 | 0.73 | MIF (0.36) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914339-A | ANTI-DIABETIC AND/OR ANTIHYPERGLYCEMIA AND/OR ANTI-OBESITY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |
| EP-0901484-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043273-A1 | SUBSTITUTED 1, 3-BENZODIOXOLES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |