Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353339 | 0.83 | LMNA (0.41) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5524384 | 0.83 | ALDH1A1 (0.50) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29421567 | 0.81 | LMNA (0.49) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL394533 | 0.81 | LMNA (0.49) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL851152 | 0.81 | CA2 (0.55) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10412670 | 0.80 | LMNA (0.61) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL711751 | 0.80 | MAPT (0.62) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17985 | 0.79 | LMNA (0.47) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL30454637 | 0.79 | LMNA (0.47) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL28558789 | 0.79 | LMNA (0.67) | LMNAMEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160151337-A1 | ANNELATED PYRROLES AND THEIR USE AS CRAC INHIBITORS | GRUENENTHAL GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| US-20160151337-A1 | ANNELATED PYRROLES AND THEIR USE AS CRAC INHIBITORS | GRUENENTHAL GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| WO-2015022073-A1 | ANNELATED PYRROLES AND THEIR USE AS CRAC INHIBITORS | Grünenthal GmbH (DE) | 2015-02-19 | — | — | WO | disclosed |
| EP-2099807-B1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSEONICS INC (US) | 2014-01-01 | — | — | EP | disclosed |
| CN-101541813-B | Oxidation resistant indicator molecules | SENSORS FOR MED & SCIENCE INC | 2013-07-31 | — | — | CN | disclosed |
| US-8143068-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143068-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143068-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-7851225-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-7851225-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-7851225-B2 | Oxidation resistant indicator molecules | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| CN-101541813-A | Oxidation resistant indicator molecules | SENSORS FOR MED & SCIENCE INC (US) | 2009-09-23 | — | — | CN | disclosed |
| EP-2099807-A2 | OXIDATION RESISTANT INDICATOR MOLECULES | Sensors For Medicine And Science, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-19 | — | — | US | disclosed |
| WO-2008066921-A2 | OXIDATION RESISTANT INDICATOR MOLECULES | SENSORS FOR MEDICINE AND SCIENCE, INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160151337-A1 | ANNELATED PYRROLES AND THEIR USE AS CRAC INHIBITORS | AADAC, PRRC2C, PRRC2A | LMNA 2660/4885MEN1 3713/4885ALDH1A1 1708/4885 |
| US-20110081727-A1 | Oxidation Resistant Indicator Molecules | AOX1, GPX4, SQOR | LMNA 3289/4885MEN1 4586/4885ALDH1A1 129/4885 |
| US-20080145944-A1 | OXIDATION RESISTANT INDICATOR MOLECULES | AOX1, GPX4, SQOR | LMNA 3289/4885MEN1 4586/4885ALDH1A1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.