Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986305 | 0.82 | KDM4E (0.53) | LMNAKDM4EHTR6HTR2ADRD2 | |
| SCHEMBL3936672 | 0.77 | HTR1A (0.46) | KDM4EMEN1KMT2A | |
| SCHEMBL6985174 | 0.77 | HTR6 (0.39) | HTR6HPGDDRD2 | |
| Oxalic Acid SCHEMBL8311341 | 0.76 | HTR2A (0.46) | HTR2AHTR2CDRD2 | |
| SCHEMBL6981092 | 0.73 | DRD3 (0.34) | LMNAMAPTHTR2CMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6982794 | 0.72 | KMT2A (0.35) | LMNAMAPTHTR2CMEN1KMT2A | |
| SCHEMBL6984897 | 0.71 | DRD3 (0.38) | KDM4EMAPTHTR2AMEN1KMT2A | |
| SCHEMBL6985365 | 0.69 | LMNA (0.42) | LMNAHPGDSMN1; SMN2DRD4 | |
| SCHEMBL6983488 | 0.69 | DRD2 (0.41) | LMNAKDM4EMAPTHTR2CMEN1 | |
| Hydrochloric Acid SCHEMBL6979044 | 0.69 | LMNA (0.41) | LMNAMAPTMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |