Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398387 | 0.81 | PTGS2 (0.53) | PTGS2PDE4BABL1MAPTTP53 | |
| SCHEMBL8311450 | 0.76 | PTGS2 (0.44) | PTGS2PDE4BABL1MAPTGAA | |
| SCHEMBL13425935 | 0.75 | PTGS2 (0.47) | PTGS2PDE4BMAPTGAACNR2 | |
| SCHEMBL8309601 | 0.72 | MAPT (0.52) | PTGS2MAPTTP53GAAKDM4E | |
| SCHEMBL8311952 | 0.70 | LMNA (0.51) | PTGS2MAPTTP53GAAKDM4E | |
| SCHEMBL8310550 | 0.68 | PTGS2 (0.48) | PTGS2PDE4BMAPTGAACNR2 | |
| SCHEMBL10960418 | 0.68 | CA12 (0.47) | ABL1CNR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL10876315 | 0.67 | L3MBTL1 (0.45) | PDE4BMAPTCNR2KDM4EMEN1 | |
| SCHEMBL14982241 | 0.66 | MAPT (0.56) | MAPTTP53GAAKDM4EMEN1 | |
| SCHEMBL3399098 | 0.65 | PDE4B (0.49) | PDE4BGAAKDM4EMAPK1F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10168063-A | — | — | None | — | — | JP | disclosed |
| JP-H10168063-A | SUBSTITUTED PYRAZOLE DERIVATIVE, ITS PRODUCTION AND ANTIMICROBIAL AGENT CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT AND USEFUL FOR AGRICULTUTE AND HORTICULTURE | SDS BIOTECH KK | 1998-06-23 | — | — | JP | disclosed |