Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317458 | 0.82 | PKM (0.49) | KMT2AMEN1CNR2ALDH1A1MAPT | |
| SCHEMBL8320461 | 0.73 | EGFR (0.52) | KMT2AMEN1TAAR1ALDH1A1MAPT | |
| SCHEMBL8321364 | 0.73 | MAPT (0.50) | KMT2AMEN1CNR2ALDH1A1MAPT | |
| SCHEMBL8320373 | 0.71 | HDAC1 (0.57) | KMT2AMEN1CNR2ALDH1A1MAPT | |
| SCHEMBL8313475 | 0.71 | ALDH1A1 (0.48) | KMT2AMEN1CNR2ALDH1A1MAPT | |
| SCHEMBL27880928 | 0.71 | EGFR (0.59) | KMT2AALDH1A1HTTHDAC3HDAC1 | |
| SCHEMBL8324894 | 0.70 | KMT2A (0.50) | KMT2AMEN1TAAR1ALDH1A1MAPT | |
| SCHEMBL8318925 | 0.70 | HDAC1 (0.53) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL8314172 | 0.70 | LMNA (0.47) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8317404 | 0.70 | SNCA (0.49) | KMT2AMEN1ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |