Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533017 | 0.86 | FFAR4 (0.55) | LMNAALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL533055 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2KDM4ERECQL | |
| SCHEMBL533437 | 0.84 | CYTH2 (0.49) | HTTLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL532880 | 0.84 | FFAR4 (0.56) | HTTLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL533666 | 0.84 | FFAR4 (0.56) | HTTLMNAALDH1A1MAPTTP53 | |
| SCHEMBL532776 | 0.84 | FFAR4 (0.54) | LMNAALDH1A1MAPTTP53RECQL | |
| SCHEMBL533091 | 0.82 | BRPF1 (0.52) | BRPF1LMNAALDH1A1MAPTTP53 | |
| SCHEMBL534816 | 0.82 | MAPT (0.41) | BRPF1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL532953 | 0.82 | FFAR4 (0.59) | ALDH1A1MAPTSMN1; SMN2FFAR4MEN1 | |
| SCHEMBL534077 | 0.82 | TSHR (0.47) | LMNAALDH1A1MAPTTP53RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073634-A2 | PHENYLENEDIAMINE UROTENSIN-II RECEPTOR ANTAGONISTS AND CCR-9 ANTAGONISTS | ENCYSIVE PHARMACEUTICALS INC. (US) | 2004-09-02 | — | — | WO | disclosed |