Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | FPR1 | P21462 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326123 | 0.82 | CTSC (0.37) | CTSCCTSKKCNH2FPR1FPR2 | |
| SCHEMBL8326340 | 0.81 | CTSC (0.43) | CTSCKCNH2 | |
| SCHEMBL8326152 | 0.71 | MC4R (0.37) | CTSCKCNH2 | |
| SCHEMBL8327687 | 0.69 | DPP4 (0.36) | CTSCDPP4FAPDPP8DPP9 | |
| SCHEMBL8329549 | 0.67 | CTSC (0.37) | CTSCKCNH2 | |
| SCHEMBL8328601 | 0.65 | BCHE (0.41) | — | |
| SCHEMBL10821633 | 0.64 | DPP4 (0.40) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL8325591 | 0.63 | OPRM1 (0.40) | — | |
| SCHEMBL8329414 | 0.62 | SIGMAR1 (0.53) | — | |
| SCHEMBL3172811 | 0.62 | HIF1A (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |