Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 4/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887289 | 0.87 | LTA4H (0.33) | LTA4HMAPTOPRK1DRD3ALDH1A1 | |
| SCHEMBL8327067 | 0.87 | LTA4H (0.33) | LTA4HMAPTOPRK1DRD3ALDH1A1 | |
| SCHEMBL8325986 | 0.85 | HRH1 (0.35) | DRD3ALDH1A1HTTKDM4EDRD2 | |
| SCHEMBL8327922 | 0.83 | BCHE (0.35) | MAPTDRD3ALDH1A1MITFHTT | |
| SCHEMBL8327173 | 0.81 | PRKAA2 (0.42) | DRD3ALDH1A1 | |
| SCHEMBL8326062 | 0.81 | HTR3A (0.30) | — | |
| SCHEMBL8328991 | 0.75 | ALDH1A1 (0.31) | MAPTALDH1A1MITFHTTRAB9A | |
| SCHEMBL8322051 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1MITFHTTRAB9A | |
| SCHEMBL8324780 | 0.73 | — | — | |
| SCHEMBL8324755 | 0.73 | SIGMAR1 (0.37) | MAPTALDH1A1MITFHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |