SCHEMBL8327907

SCHEMBL8327907

CC(C)OP(=O)([O-])C#N.[Na+]

nearest known ligand 0.39

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.39
ACHE P22303 1/20 0.39
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL8330745 0.95 CTSA (0.39) CTSAACHEALDH1A1L3MBTL1
Phosphorylisopropane SCHEMBL31213517 0.73 CTSA (0.50) CTSAACHEALDH1A1L3MBTL1
SCHEMBL4096902 0.72 CTSA (0.43) CTSAACHEALDH1A1L3MBTL1
SCHEMBL7572066 0.72
Phosphorylisopropane SCHEMBL31314215 0.71 CTSA (0.48) CTSAACHEALDH1A1L3MBTL1
Phosphorylisopropane SCHEMBL7157553 0.71 CTSA (0.48) CTSAACHEALDH1A1L3MBTL1
Phosphorylisopropane SCHEMBL28777354 0.71 CTSA (0.48) CTSAACHEALDH1A1L3MBTL1
SCHEMBL30579940 0.71 CTSA (0.48) CTSAACHEALDH1A1L3MBTL1
Phosphorylisopropane SCHEMBL28777332 0.71
SCHEMBL11658228 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948505-A1 HYDROGENATION OF MIXTURES OF CYANOPHOSPHONATES AND GLYCINE MONSANTO COMPANY (US) 1999-10-13 EP disclosed
US-5859290-A Hydrogenation of cyanophosphonate derivatives in the presence of a glycine derivative MONSANTO COMPANY (US) 1999-01-12 US disclosed
WO-1998029421-A1 HYDROGENATION OF MIXTURES OF CYANOPHOSPHONATES AND GLYCINE MONSANTO COMPANY (US) 1998-07-09 WO disclosed