Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | STK4 | Q13043 | 1/20 | 0.30 |
| ▸ | STK3 | Q13188 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329028 | 0.83 | THRB (0.38) | THRBMEN1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL8670100 | 0.82 | THRB (0.36) | THRBXDHDPP4MEN1HTT | |
| SCHEMBL8327888 | 0.79 | MAPT (0.38) | MEN1KMT2ASTK4 | |
| SCHEMBL8325615 | 0.79 | THRB (0.47) | THRBDPP4 | |
| Hydrochloric Acid SCHEMBL8323048 | 0.77 | THRB (0.46) | THRBDPP4 | |
| SCHEMBL8330323 | 0.77 | MAPK8 (0.42) | — | |
| SCHEMBL8328091 | 0.75 | SYK (0.38) | MEN1KMT2ASTK3 | |
| SCHEMBL8328465 | 0.73 | PTGS2 (0.40) | KMT2A | |
| SCHEMBL8324245 | 0.66 | TSHR (0.42) | DPP4 | |
| SCHEMBL8329054 | 0.64 | MAPT (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |