Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328988 | 0.86 | KDM4E (0.31) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8328585 | 0.84 | ALDH1A1 (0.34) | ALDH1A1KDM4ENPSR1SIGMAR1 | |
| SCHEMBL8328371 | 0.82 | NOS3 (0.35) | — | |
| SCHEMBL8328415 | 0.81 | GSK3B (0.36) | SIGMAR1 | |
| SCHEMBL8326581 | 0.78 | SPHK2 (0.34) | ALDH1A1NPSR1 | |
| SCHEMBL8326763 | 0.76 | DRD4 (0.41) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8321742 | 0.72 | PKM (0.37) | ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL8328809 | 0.72 | POLB (0.38) | ALDH1A1KDM4EACHESIGMAR1 | |
| SCHEMBL8327461 | 0.70 | ALDH1A1 (0.32) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8327681 | 0.70 | DRD4 (0.41) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |