Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332092 | 0.81 | NFKB1 (0.33) | NFKB1NFKB2RELAMETAP2 | |
| SCHEMBL11005384 | 0.77 | CYP1A2 (0.42) | METAP2 | |
| SCHEMBL8332090 | 0.76 | METAP2 (0.38) | METAP2 | |
| SCHEMBL8328919 | 0.76 | EPHX1 (0.46) | METAP2 | |
| SCHEMBL8328587 | 0.76 | EPHX1 (0.33) | METAP2 | |
| SCHEMBL8327178 | 0.76 | BCHE (0.39) | METAP2 | |
| SCHEMBL8328926 | 0.75 | METAP2 (0.38) | METAP2 | |
| SCHEMBL8331541 | 0.75 | SIGMAR1 (0.38) | METAP2 | |
| SCHEMBL8328594 | 0.75 | REN (0.39) | METAP2 | |
| SCHEMBL8329946 | 0.75 | EPHX1 (0.49) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |