Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 1.00 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.73 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.73 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | PIM1 | P11309 | 5/20 | 0.52 |
| ▸ | GSK3A | P49840 | 3/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 3/20 | 0.47 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176935 | 0.90 | TLR8 (0.82) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL8336450 | 0.85 | TLR8 (0.74) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL8335009 | 0.85 | TLR8 (0.73) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL8338772 | 0.84 | CLK4 (1.00) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL3155668 | 0.84 | TLR8 (0.72) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL10336150 | 0.83 | TLR8 (0.71) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL8435070 | 0.82 | KDM4E (1.00) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL9729664 | 0.81 | TLR8 (0.68) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL9728658 | 0.81 | MAP2K1 (0.78) | TLR8MAP2K1CLK4DYRK1BKDM4E | |
| SCHEMBL9877202 | 0.80 | TLR8 (0.67) | TLR8MAP2K1CLK4DYRK1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014092-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION | AGS THERAPEUTICS SAS (FR) | 2026-01-15 | — | — | US | claimed |
| WO-2024194423-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION | AGS THERAPEUTICS SAS (FR) | 2024-09-26 | — | — | WO | claimed |
| US-20260014092-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION | AGS THERAPEUTICS SAS (FR) | 2026-01-15 | — | — | US | disclosed |
| US-20240423923-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR BIODISTRIBUTION UPON ADMINISTRATION, AND USES | AGS THERAPEUTICS SAS (FR) | 2024-12-26 | — | — | US | disclosed |
| WO-2024194423-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION | AGS THERAPEUTICS SAS (FR) | 2024-09-26 | — | — | WO | disclosed |
| CN-117586108-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586191-A | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2024-02-23 | — | — | CN | disclosed |
| US-20230414678-A1 | SHELF- STABLE AMMONIA OXIDIZING MICROORGANISM PREPARATIONS | AOBIOME LLC (US) | 2023-12-28 | — | — | US | disclosed |
| CN-111542515-B | TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof | 科罗拉多州立大学董事会法人团体 | 2023-12-05 | — | — | CN | disclosed |
| CN-116782924-A | Storage-stable ammoxidation microbial preparation | AO生物医学有限责任公司 | 2023-09-19 | — | — | CN | disclosed |
| US-20230201274-A1 | SHELF- STABLE AMMONIA OXIDIZING MICROORGANISM PREPARATIONS | AOBIOME LLC (US) | 2023-06-29 | — | — | US | disclosed |
| US-20210179621-A1 | Toll-Like Receptor 8 (TLR8) Specific Antagonists and Methods of Making and Uses Thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2021-06-17 | — | — | US | disclosed |
| EP-0957918-A1 | METHOD OF TREATING OR INHIBITING NEUTROPENIA | American Cyanamid Company (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5932585-A | Method of treating or inhibiting neutropenia | AMERICAN CYANAMID COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1998026781-A1 | METHOD OF TREATING OR INHIBITING NEUTROPENIA | AMERICAN CYANAMID COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |
| EP-0329940-B1 | 5-(substituted)amino)-8- (phenyl or substituted phenyl)-3H,6H-1,2,5,a,8 a-tetraazaacenaphthylen-3-ones | AMERICAN CYANAMID CO (US) | 1994-01-05 | — | — | EP | disclosed |
| US-5169850-A | Neurotropic or hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | disclosed |
| US-4916137-A | 5-(Substituted-amino)-8-(phenyl or substituted-phenyl)-3H,6H-1,4,5A,8A-tetraazaacenaphthylen-3-ones and treatment of neural behavior disorders | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| EP-0329940-A1 | 5-(substituted)amino)-8- (phenyl or substituted phenyl)-3H,6H-1,2,5,a,8 a-tetraazaacenaphthylen-3-ones | AMERICAN CYANAMID COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201274-A1 | SHELF- STABLE AMMONIA OXIDIZING MICROORGANISM PREPARATIONS | SI, OTC, APC | TLR8 392/4885MAP2K1 4345/4885CLK4 4392/4885 |
| US-20260014092-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION | TLR9, TLR1, TLR2 | TLR8 7/4885MAP2K1 2910/4885CLK4 1476/4885 |
| US-20240423923-A1 | EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR BIODISTRIBUTION UPON ADMINISTRATION, AND USES | CHMP4B, ALG1, FUCA2 | TLR8 654/4885MAP2K1 4456/4885CLK4 2225/4885 |
| US-20210179621-A1 | Toll-Like Receptor 8 (TLR8) Specific Antagonists and Methods of Making and Uses Thereof | TLR8, TLR3, TLR9 | TLR8 1/4885MAP2K1 2248/4885CLK4 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.