Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097916 | 0.86 | CES2 (0.53) | CYP1A2NPC1CYP2C9CYP2C19RAB9A | |
| SCHEMBL8734502 | 0.84 | NR1H4 (0.53) | HPGDCYP1A2NPC1CYP2C9CYP2C19 | |
| SCHEMBL77601 | 0.82 | MAPT (0.53) | HPGDALDH1A1KDM4EMAPTF3 | |
| SCHEMBL13810256 | 0.82 | MEN1 (0.58) | HPGDCYP1A2CYP2C9SMN1; SMN2ALDH1A1 | |
| SCHEMBL8737494 | 0.82 | TAS1R3 (0.47) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31457368 | 0.81 | KDM4E (0.46) | HPGDCYP1A2NPC1CYP2C9CYP2C19 | |
| SCHEMBL4007797 | 0.81 | MEN1 (0.41) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8735315 | 0.80 | MEN1 (0.48) | CYP1A2NPC1CYP2C9CYP2C19RAB9A | |
| SCHEMBL8737497 | 0.80 | NR1H4 (0.47) | TSHR | |
| SCHEMBL21457595 | 0.80 | ALDH1A1 (0.59) | HPGDCYP1A2SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848947-B1 | Compositions containing a derivative of dibenzoylmethane, a derivative of 1,3,4-triazine and an dialkly benyalmalonate | OREAL (FR) | 1999-08-11 | — | — | EP | claimed |
| US-5882634-A | COSMETICS AND SKINS | SOCIETE L'OREAL S.A. (FR) | 1999-03-16 | — | — | US | claimed |
| US-5670140-A | SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE | L'OREAL (FR) | 1997-09-23 | — | — | US | claimed |
| US-5624663-A | Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates | L'OREAL (FR) | 1997-04-29 | — | — | US | claimed |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
| US-20120128745-A1 | BENZYLIDENE MALONATES | BASF SE (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120128745-A1 | BENZYLIDENE MALONATES | BASF SE (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2010136360-A2 | BENZYLIDENE MALONATES | BASF SE (DE) | 2010-12-02 | — | — | WO | disclosed |
| US-5882634-A | COSMETICS AND SKINS | SOCIETE L'OREAL S.A. (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5670140-A | SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE | L'OREAL (FR) | 1997-09-23 | — | — | US | disclosed |
| US-5624663-A | Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates | L'OREAL (FR) | 1997-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128745-A1 | BENZYLIDENE MALONATES | TERT, REL, MGMT | HPGD 1283/4885CYP1A2 871/4885NPC1 2557/4885 |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | HPGD 1130/4885CYP1A2 1758/4885NPC1 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.