Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345912 | 0.91 | NPC1 (0.43) | NPC1RAB9AHPGDSMN1; SMN2MRGPRX4 | |
| SCHEMBL8344663 | 0.78 | MAPT (0.51) | NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8344558 | 0.74 | MAOB (0.50) | NPC1RAB9AHPGDSMN1; SMN2MAOB | |
| SCHEMBL20199977 | 0.70 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL17191283 | 0.69 | BACE1 (0.47) | SMN1; SMN2HDAC8 | |
| SCHEMBL25798559 | 0.69 | HDAC8 (0.50) | NPC1RAB9ASMN1; SMN2MAOBCCR5 | |
| SCHEMBL23017937 | 0.68 | CCR5 (0.50) | NPC1RAB9ASMN1; SMN2MAOBCCR5 | |
| SCHEMBL2519601 | 0.68 | LMNA (0.54) | RAB9ASMN1; SMN2MAOB | |
| SCHEMBL20359857 | 0.68 | MAPT (0.49) | NPC1RAB9ASMN1; SMN2MRGPRX4MAOB | |
| SCHEMBL16199730 | 0.68 | LOXL2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874511-A | CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-23 | — | — | US | claimed |
| US-5932675-A | Free-radical chain transfer polymerization process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-08-03 | — | — | US | disclosed |
| US-5874511-A | CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-23 | — | — | US | disclosed |