Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553152 | 0.88 | — | — | |
| SCHEMBL2553157 | 0.88 | — | — | |
| SCHEMBL12983433 | 0.83 | ITGB3 (0.40) | ITGB3ITGB1ITGAVITGA4TSHR | |
| SCHEMBL1773442 | 0.78 | — | — | |
| SCHEMBL620598 | 0.78 | — | — | |
| SCHEMBL14854669 | 0.77 | MAOA (0.34) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5245447 | 0.77 | CHRNB2 (0.35) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16510369 | 0.77 | HRH3 (0.31) | TSHRGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1308184 | 0.76 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4TSHR | |
| SCHEMBL30601862 | 0.76 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2020207474-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2020-10-15 | — | — | WO | disclosed |
| WO-2018021977-A1 | GLYCINE METABOLISM MODULATORS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-02-01 | — | — | WO | disclosed |
| EP-2661424-B1 | 4-(ORTHO-SUBSTITUTED-PHENYL)-5-OXO-2,5-DIHYDRO-1H-PYRROLE COMPOUNDS AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-12 | — | — | EP | disclosed |
| US-8383839-B2 | Heterocyclidene acetamide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2013-02-26 | — | — | US | disclosed |
| US-20110112071-A1 | NOVEL HETEROCYCLIDENE ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-05-12 | — | — | US | disclosed |
| US-7910751-B2 | Heterocyclidene acetamide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20080287428-A1 | Novel Heterocyclidene Acetamide Derivative | MOCHIDA PHARMACEUTICAL CO.,LTD (JP) | 2008-11-20 | — | — | US | disclosed |
| US-20080153801-A1 | Benzoxazepine compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2008-06-26 | — | — | US | disclosed |
| US-20080153801-A1 | Benzoxazepine compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2008-06-26 | — | — | US | disclosed |
| US-20070117787-A1 | Benzoxazepine compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2007-05-24 | — | — | US | disclosed |
| US-20070117787-A1 | Benzoxazepine compounds, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2007-05-24 | — | — | US | disclosed |
| WO-1999029705-A2 | SIALYL LEWIS X AND SIALYL LEWIS A GLYCOMIMETICS | GLYCOMED INCORPORATED (US) | 1999-06-17 | — | — | WO | disclosed |
| US-4130710-A | POLYOLEFIN STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |
| US-3971795-A | POLYMER STABILIZER | CIBA-GEIGY CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117787-A1 | Benzoxazepine compounds, their production and use | NR1H2, APOB, CETP | ITGB3 4830/4885ITGB1 4798/4885ITGAV 4860/4885 |
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | ITGB3 1152/4885ITGB1 2209/4885ITGAV 3219/4885 |
| US-20080287428-A1 | Novel Heterocyclidene Acetamide Derivative | TRPV1, TRPV3, TRPA1 | ITGB3 1419/4885ITGB1 2578/4885ITGAV 2485/4885 |
| US-20080153801-A1 | Benzoxazepine compounds, their production and use | CETP, PCSK9, LPL | ITGB3 4789/4885ITGB1 4688/4885ITGAV 4809/4885 |
| US-20110112071-A1 | NOVEL HETEROCYCLIDENE ACETAMIDE DERIVATIVE | TRPV1, TRPV3, TRPA1 | ITGB3 1419/4885ITGB1 2578/4885ITGAV 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.