Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379224 | 0.86 | ALDH1A1 (0.54) | VCAM1HPGDMAPTALDH1A1NPSR1 | |
| SCHEMBL8379051 | 0.84 | VCAM1 (0.43) | VCAM1HPGDMAPTRAB9AALDH1A1 | |
| SCHEMBL8379048 | 0.84 | VCAM1 (0.43) | VCAM1HPGDMAPTRAB9AALDH1A1 | |
| SCHEMBL8072805 | 0.82 | SMN1; SMN2 (0.51) | HPGDMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL8186035 | 0.81 | KMT2A (0.47) | VCAM1HPGDMAPTALDH1A1NPSR1 | |
| SCHEMBL8729586 | 0.81 | SMN1; SMN2 (0.57) | VCAM1HPGDMAPTALDH1A1NPSR1 | |
| SCHEMBL8816962 | 0.81 | MAOB (0.49) | HPGDMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL8068481 | 0.81 | THRA (0.43) | VCAM1HPGDRAB9AALDH1A1NPSR1 | |
| SCHEMBL8379266 | 0.80 | HPGD (0.41) | HPGDMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL8379275 | 0.80 | SLC9A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6345643-A | — | — | None | — | — | JP | disclosed |
| US-5880156-A | ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| JP-H06345643-A | SUBSTITUTED BENZOYLGUANIDINE, ITS PRODUCTION, ITS USE AS MEDICINE OR DIAGNOSTIC MEDICINE AND MEDICINE CONTAINING THE SAME | HOECHST AG | 1994-12-20 | — | — | JP | disclosed |