Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.67 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457257 | 1.00 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| SCHEMBL11656700 | 1.00 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| SCHEMBL10815605 | 1.00 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| SCHEMBL28808939 | 1.00 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| SCHEMBL10406238 | 1.00 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| SCHEMBL29662052 | 1.00 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| SCHEMBL303601 | 0.98 | CA1 (0.70) | CA1NFKB1GPR84CA2KDM4C | |
| Zinc Ion SCHEMBL27829213 | 0.95 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| Methyl Alcohol SCHEMBL27994833 | 0.95 | CA1 (0.67) | CA1NFKB1GPR84CA2KDM4C | |
| Potassium Ion SCHEMBL25191979 | 0.95 | CA1 (0.62) | CA1NFKB1GPR84KDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905264-A1 | Recovery of precious metal | HENKEL CORPORATION (US) | 1999-03-31 | — | — | EP | claimed |
| EP-0630418-A1 | RECOVERY OF PRECIOUS METAL | HENKEL CORPORATION (US) | 1994-12-28 | — | — | EP | claimed |
| US-5340380-A | Using ion exchange resin with guanidine funcionality, eluting with caustic containing acid salt modifiers; gold and silver | HENKEL CORPORATION (US) | 1994-08-23 | — | — | US | claimed |
| WO-1993019212-A2 | RECOVERY OF PRECIOUS METAL | HENKEL CORPORATION (US) | 1993-09-30 | — | — | WO | claimed |
| US-4097403-A | SORBITOL MODIFIED POLYOXYETHYLENE GLYCOL ISOALKANOATE | KAO SOAP CO., LTD. (JA) | 1978-06-27 | — | — | US | claimed |
| EP-0905264-A1 | Recovery of precious metal | HENKEL CORPORATION (US) | 1999-03-31 | — | — | EP | disclosed |