Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383409 | 0.89 | LMNA (0.56) | ALOX15FFAR1SMN1; SMN2PTPN7ALDH1A1 | |
| SCHEMBL8379886 | 0.86 | GAA (0.47) | ALOX15SMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL8384111 | 0.86 | PPARA (0.55) | FFAR1PPARGFFAR4 | |
| SCHEMBL8385005 | 0.84 | LTB4R (0.49) | ALOX15FFAR1ALDH1A1PPARDPKM | |
| SCHEMBL8385001 | 0.84 | L3MBTL1 (0.56) | ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL8385011 | 0.84 | PKM (0.67) | ALOX15ALDH1A1PKMPLA2G4B | |
| SCHEMBL8385078 | 0.82 | FFAR1 (0.68) | FFAR1PPARGPPARDFFAR4 | |
| SCHEMBL8381057 | 0.81 | LMNA (0.52) | SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL8385010 | 0.81 | ELANE (0.50) | SMN1; SMN2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8385027 | 0.80 | FFAR1 (0.63) | FFAR1SMN1; SMN2CYP1A2PPARGFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874436-A | EFFECTIVE IN INHIBITING THE ACTION OF A BACTERIAL HISTIDINE PROTEIN KINASE; USEFUL AGAINST ANTIBIOTIC RESISTANT ORGANISMS | DEMERS JAMES P (US) | 1999-02-23 | — | — | US | disclosed |
| US-5643950-A | INHIBITORS OF A BACTERIAL HISTIDINE PROTEIN KINASE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |