Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391795 | 0.89 | CYP2C9 (0.39) | MGLLCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL8390891 | 0.80 | MGLL (0.43) | MGLLCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL8489221 | 0.73 | SLC9A1 (0.40) | MGLL | |
| SCHEMBL8388424 | 0.71 | MGLL (0.42) | MGLLCYP2C9CYP2C19MAPK14CCR5 | |
| SCHEMBL8494381 | 0.65 | LMNA (0.37) | MGLL | |
| SCHEMBL8494772 | 0.62 | CNR2 (0.36) | MGLLCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL13282181 | 0.61 | MGLL (0.44) | MGLLCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL21740905 | 0.61 | CYP2C9 (0.63) | MGLLCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL8606607 | 0.61 | LMNA (0.43) | MGLL | |
| SCHEMBL4618974 | 0.60 | CYP2C9 (0.66) | MGLLCYP2C9CYP2C19HTR2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856274-A | 4-benzoyl isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |