Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336209 | 0.89 | GPR88 (0.35) | GPR88CNR2ALDH1A1UTS2RKMT2A | |
| SCHEMBL8336540 | 0.88 | CNR2 (0.40) | GPR88CNR2ALDH1A1KMT2AOPRM1 | |
| SCHEMBL8337030 | 0.87 | MMP1 (0.35) | GPR88CNR2HDAC1HDAC7OPRM1 | |
| SCHEMBL8334276 | 0.83 | ALOX5 (0.34) | GPR88CNR2ALDH1A1UTS2RKMT2A | |
| SCHEMBL8340209 | 0.81 | ADAM17 (0.36) | GPR88CNR2ALDH1A1KMT2AHDAC1 | |
| SCHEMBL8339477 | 0.80 | GPR88 (0.40) | GPR88CNR2ALDH1A1KMT2AHDAC1 | |
| SCHEMBL8338348 | 0.78 | TDP1 (0.39) | GPR88CNR2ALDH1A1KMT2AHDAC1 | |
| SCHEMBL8339611 | 0.77 | — | — | |
| SCHEMBL8335851 | 0.76 | CNR2 (0.38) | GPR88CNR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8338167 | 0.74 | HPGD (0.39) | GPR88CNR2OPRM1OPRD1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |