Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KDM6A | O15550 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TAF1 | P21675 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3119373 | 0.98 | KDM4E (0.36) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| Sulfuric Acid SCHEMBL3398193 | 0.87 | KDM4E (0.34) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL1923338 | 0.76 | KDM4E (0.36) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL2525810 | 0.73 | LPO (0.35) | KDM4EAPOBEC3AAPOBEC3GMAPT | |
| SCHEMBL839103 | 0.64 | ALOX15 (0.30) | — | |
| SCHEMBL1277062 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL8672192 | 0.61 | SMN1; SMN2 (0.38) | KDM4ELMNAMAPTSMN1; SMN2L3MBTL1 | |
| Water SCHEMBL22654522 | 0.61 | ACHE (0.35) | KDM4ELMNAMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL13367986 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL3171274 | 0.59 | HDAC8 (0.38) | KDM4EAPOBEC3AAPOBEC3GL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358343-B1 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO KGAA (DE) | 2016-10-19 | — | — | EP | claimed |
| EP-1965753-B1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO KGAA (DE) | 2013-09-04 | — | — | EP | claimed |
| US-8268015-B2 | Method for decolorizing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2012-09-18 | — | — | US | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | HENKEL AG & CO. KGAA (DE) | 2011-10-13 | — | — | US | claimed |
| US-7799096-B2 | Agent for dyeing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2010-09-21 | — | — | US | claimed |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | claimed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | claimed |
| EP-1796627-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2009-03-04 | — | — | EP | claimed |
| EP-2018844-A2 | Agent for dying fibres which contain keratin comprising derivatives of naphthaldehyde in combination with CH acidic compounds | Henkel AG & Co. KGaA (DE) | 2009-01-28 | — | — | EP | claimed |
| EP-2014275-A2 | Kit for preparing storage-stable formulations | Henkel AG & Co. KGaA (DE) | 2009-01-14 | — | — | EP | claimed |
| US-7473280-B2 | Coloring agent compositions and methods of treating keratin fibers therewith | HENKEL KGAA (DE) | 2009-01-06 | — | — | US | claimed |
| US-20080301885-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO. KGAA (DE) | 2008-12-11 | — | — | US | claimed |
| US-20080189877-A1 | Mixture of quaternized imidazo[1,5-a]pyrimidinium derivate and benzaldehyde derivative; cationic hair dyes, oxidation color dyes; colorfastness, washfastness | HENKEL KGAA (DE) | 2008-08-14 | — | — | US | claimed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | claimed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | claimed |
| EP-1789014-B1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KGAA (DE) | 2008-02-27 | — | — | EP | claimed |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | HENKEL KGAA (DE) | 2007-12-13 | — | — | US | claimed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | KRT18, PLOD3, DSG1 | KDM4E 508/4885KDM6A 101/4885KDM4A 498/4885 |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | KRT18, KAT5, H1-5 | KDM4E 1661/4885KDM6A 580/4885KDM4A 1062/4885 |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | KRT18, SCNN1B, COL1A1 | KDM4E 615/4885KDM6A 457/4885KDM4A 470/4885 |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | KRT18, CRYAA, CKAP4 | KDM4E 1842/4885KDM6A 463/4885KDM4A 1045/4885 |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | KDM4E 1659/4885KDM6A 788/4885KDM4A 778/4885 |
| US-20080301885-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | TYR, CBR3, COXFA4L2 | KDM4E 707/4885KDM6A 366/4885KDM4A 535/4885 |
| US-20080189877-A1 | Mixture of quaternized imidazo[1,5-a]pyrimidinium derivate and benzaldehyde derivative; cationic hair dyes, oxidation color dyes; colorfastness, washfastness | TYR, NDUFS5, WASHC5 | KDM4E 1235/4885KDM6A 1150/4885KDM4A 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.