Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395549 | 0.83 | PDE4A (0.31) | — | |
| SCHEMBL8397063 | 0.82 | AKR1B1 (0.37) | AKR1B1 | |
| SCHEMBL8400189 | 0.79 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL8395366 | 0.74 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL8395489 | 0.71 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL8399262 | 0.71 | AKR1B1 (0.40) | AKR1B1 | |
| SCHEMBL8399294 | 0.71 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL8399351 | 0.70 | AKR1B1 (0.46) | AKR1B1 | |
| SCHEMBL8399620 | 0.70 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL8399269 | 0.70 | MAPT (0.38) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |