Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401465 | 0.80 | ALDH1A1 (0.76) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL8399433 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL8399519 | 0.76 | USP2 (0.37) | ALDH1A1MAPTKMT2AMEN1RECQL | |
| SCHEMBL8399558 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL11052582 | 0.72 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL8403524 | 0.71 | APLNR (0.45) | ALDH1A1MAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL16956854 | 0.69 | SMN1; SMN2 (0.55) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL14601545 | 0.66 | ALDH1A1 (0.63) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL16861184 | 0.65 | GPR35 (0.51) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL22366682 | 0.65 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885997-A | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-23 | — | — | US | disclosed |