Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409450 | 0.94 | KDM1A (0.40) | HRH2HRH1KDM1AEGLN1 | |
| SCHEMBL8407652 | 0.94 | HRH2 (0.45) | HRH2HRH1KDM1AFFAR4CETP | |
| SCHEMBL8409543 | 0.89 | KDM1A (0.41) | HRH2HRH1KDM1AUSP14 | |
| SCHEMBL8718962 | 0.85 | CHRM4 (0.38) | KDM1ASIGMAR1ERAP1CHRM4 | |
| SCHEMBL8407515 | 0.80 | KDM1A (0.38) | KDM1A | |
| SCHEMBL9170067 | 0.80 | SIGMAR1 (0.59) | SIGMAR1CHRM4CTSSCTSK | |
| SCHEMBL9174372 | 0.78 | CTSS (0.48) | KDM1ASIGMAR1CHRM4CTSSCTSK | |
| SCHEMBL9175929 | 0.78 | CTSS (0.50) | SIGMAR1CHRM4CTSSCTSK | |
| SCHEMBL7753345 | 0.77 | USP14 (0.52) | FFAR4USP14SIGMAR1CHRM4CTSS | |
| SCHEMBL8407178 | 0.76 | KDM1A (0.38) | KDM1AUSP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5736559-A | CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS | KARL THOMAE GMBH (DE) | 1998-04-07 | — | — | US | disclosed |