Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 3/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175929 | 0.87 | CTSS (0.50) | CTSSCTSKCHRM4DPP4SIGMAR1 | |
| SCHEMBL9175913 | 0.85 | CHRM4 (0.51) | CHRM4TACR3DPP4 | |
| Hydrochloric Acid SCHEMBL9175742 | 0.85 | CHRM4 (0.51) | CHRM4TACR3DPP4 | |
| SCHEMBL9170067 | 0.84 | SIGMAR1 (0.59) | CTSSCTSKCHRM4MEN1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9173150 | 0.83 | CA12 (0.42) | MEN1TDP1MAPTMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9173969 | 0.81 | ITGB3 (0.46) | MEN1MAPTALDH1A1KMT2A | |
| SCHEMBL9174730 | 0.80 | ALDH1A1 (0.43) | MEN1TDP1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7753345 | 0.79 | USP14 (0.52) | CTSSCTSKCHRM4MEN1TDP1 | |
| SCHEMBL8407654 | 0.78 | HRH2 (0.41) | CTSSCTSKCHRM4KDM1ASIGMAR1 | |
| SCHEMBL8407652 | 0.78 | HRH2 (0.45) | CTSSCTSKCHRM4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442064-A | Anticoagulants, antiagglomerants | DR. KARL THOMAE GMBH (DE) | 1995-08-15 | — | — | US | disclosed |
| EP-0592949-A2 | N-(aminocarbonyl)-piperidines/pepirazines as aggregation inhibiting agents | Dr. Karl Thomae GmbH (DE) | 1994-04-20 | — | — | EP | disclosed |