Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | STK10 | O94804 | 1/20 | 0.36 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412577 | 0.82 | SLC9A1 (0.38) | CCR2STK10SLKPTPN1P2RX7 | |
| SCHEMBL8412574 | 0.82 | CCR2 (0.36) | CCR2STK10SLKPTPN1P2RX7 | |
| SCHEMBL9069065 | 0.82 | TRPV4 (0.41) | P2RX7MEN1KMT2ATRPV4CYP1A2 | |
| SCHEMBL8409006 | 0.77 | MEN1 (0.42) | P2RX7MEN1KMT2ATRPV4CYP1A2 | |
| SCHEMBL8409405 | 0.77 | PKM (0.39) | CCR2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8412670 | 0.77 | STK10 (0.36) | CCR2STK10SLKPTPN1P2RX7 | |
| SCHEMBL30586543 | 0.75 | SLC22A12 (0.42) | MEN1KMT2ATRPV4CYP1A2CYP3A4 | |
| SCHEMBL8412945 | 0.75 | ALDH1A1 (0.38) | CCR2MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL30605923 | 0.75 | MCL1 (0.43) | P2RX7MEN1KMT2ATRPV4SMN1; SMN2 | |
| SCHEMBL1501184 | 0.75 | SLC22A12 (0.42) | MEN1KMT2ATRPV4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |