Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | PKLR | P30613 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734275 | 0.81 | PTGES2 (0.46) | PKMPKLRSMN1; SMN2ALDH1A1PTGES2 | |
| SCHEMBL8412700 | 0.81 | PKM (0.36) | PKMPKLRALDH1A1HPGDMAPT | |
| SCHEMBL8412568 | 0.80 | PKM (0.38) | PKMPKLRSMN1; SMN2ALDH1A1PTGES2 | |
| SCHEMBL8412570 | 0.80 | PKM (0.38) | PKMPKLRSMN1; SMN2ALDH1A1PTGES2 | |
| SCHEMBL532887 | 0.80 | PKM (0.50) | PKMPKLRALDH1A1PTGES2LMNA | |
| SCHEMBL8412945 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1CCR2KMT2AMAPT | |
| SCHEMBL8409259 | 0.77 | CCR2 (0.36) | SMN1; SMN2ALDH1A1CCR2KMT2AMEN1 | |
| SCHEMBL8409383 | 0.76 | GABRA1 (0.36) | SMN1; SMN2ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL8412954 | 0.75 | PKM (0.34) | PKMPKLRSMN1; SMN2ALDH1A1PTGES2 | |
| SCHEMBL29764209 | 0.75 | ACHE (0.44) | PKMPKLRALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1339432-A | Extracting method for substituted phenyl compounds | ROHM & HAAS (US) | 2002-03-13 | — | — | CN | disclosed |
| CN-1070175-C | Process for the preparation of 2, 6-disubstituted benzenesulfonates or 2, 6-disubstituted benzenesulfonates further substituted in the 3-, 4-or 5-position | ROHM & HAAS (US) | 2001-08-29 | — | — | CN | disclosed |
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| CN-1174189-A | Process for preparing substituted benzene compounds | ROHM & HAAS (US) | 1998-02-25 | — | — | CN | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |