Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410334 | 0.84 | ALDH1A1 (0.39) | SIGMAR1ADH1BADH1CADH1AADH7 | |
| SCHEMBL8407070 | 0.84 | ADH1B (0.38) | FKBP1ALMNAADH1BADH1CADH1A | |
| SCHEMBL5071627 | 0.73 | CYP1A2 (0.37) | TAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL8410043 | 0.70 | OPRM1 (0.55) | FKBP1ALMNASIGMAR1POLBALDH1A1 | |
| SCHEMBL8070720 | 0.69 | ADRB2 (0.48) | LMNAADH1BADH1CADH1AADH7 | |
| SCHEMBL28872341 | 0.69 | HDAC1 (0.45) | LMNAMAPTALDH1A1TSHR | |
| SCHEMBL8059353 | 0.68 | ADRB2 (0.50) | LMNAADH1BADH1CADH1AADH7 | |
| SCHEMBL2084466 | 0.68 | DPP4 (0.38) | — | |
| SCHEMBL12346120 | 0.65 | L3MBTL1 (0.40) | SIGMAR1POLBALDH1A1TSHRMEN1 | |
| SCHEMBL2437772 | 0.64 | ALDH1A1 (0.38) | SIGMAR1ALDH1A1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962469-A | PREVENTION OF OXIDATION TISSUE DAMAGE BY FREE RADICALS | HOECHST MARION ROUSSEL INC. (US) | 1999-10-05 | — | — | US | disclosed |