SCHEMBL841041

SCHEMBL841041

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n1ccnc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 1/20 0.35
PGR P06401 1/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
RORB Q92753 1/20 0.35
TNKS O95271 1/20 0.35
KMT2A Q03164 3/20 0.34
IKBKB O14920 1/20 0.34
PARP1 P09874 1/20 0.33
KCNH2 Q12809 1/20 0.33
TACR1 P25103 2/20 0.33
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
KIF11 P52732 3/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12756766 0.91 PGR (0.45) HTR1DPGRRORARORCRORB
SCHEMBL22280693 0.86 RORA (0.35) HTR1DPGRRORARORCRORB
SCHEMBL22280692 0.85 FGFR2 (0.36) PGRRORARORCRORBKMT2A
SCHEMBL22281106 0.84 CASR (0.40) PGRRORARORCRORBKMT2A
SCHEMBL22280928 0.82 PPARG (0.36) PGRRORARORCRORBKMT2A
SCHEMBL22281105 0.80 PGR (0.37) PGRRORARORCRORBKMT2A
SCHEMBL9971729 0.78 HTR3E (0.45) KMT2AIKBKBPARP1TACR1HTR3E
SCHEMBL22262070 0.77 LMNA (0.35) RORARORCRORBTNKSKMT2A
SCHEMBL22280926 0.76 FGFR2 (0.36) TNKSKMT2AMEN1POLBALDH1A1
SCHEMBL14475301 0.76 HRH4 (0.38) TNKSKMT2AIKBKBKCNH2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP disclosed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US disclosed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP disclosed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US disclosed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP disclosed
EP-1981898-B2 Metal complexes of imidazo[1,2-f]phenanthridine ligands for use in OLED devices UNIVERSAL DISPLAY CORP (US) 2019-04-10 EP disclosed
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-21 US disclosed
US-20130310561-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-f ) PHENANTHRIDINE AND DIIMIDAZO (1,2-a:1', 2'-c),QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2013-11-21 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
EP-2399922-A1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof Universal Display Corporation (US) 2011-12-28 EP disclosed
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF KNOWLES DAVID B 2011-03-31 US disclosed
US-7915415-B2 Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION (US) 2011-03-29 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
EP-2243785-A1 Phosphorescent condensed ring carbene metal complexes for use in organic light emitting devices Universal Display Corporation (US) 2010-10-27 EP disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF NDUFC1, CD274, CRY1 HTR1D 13/4885PGR 3835/4885RORA 1412/4885
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 HTR1D 819/4885PGR 3542/4885RORA 1943/4885
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 HTR1D 819/4885PGR 3542/4885RORA 1943/4885
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE ZFR, PORCN, OR10J3 HTR1D 4644/4885PGR 3202/4885RORA 2945/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 HTR1D 1944/4885PGR 377/4885RORA 642/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C HTR1D 649/4885PGR 3621/4885RORA 2304/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 HTR1D 819/4885PGR 3542/4885RORA 1943/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 HTR1D 819/4885PGR 3542/4885RORA 1943/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 HTR1D 1944/4885PGR 377/4885RORA 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.