Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413215 | 0.91 | HTR1A (0.38) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL8519203 | 0.83 | DRD2 (0.39) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL8413058 | 0.83 | HTR7 (0.36) | HTR7DRD2KDM4EALDH1A1MAPT | |
| SCHEMBL8410575 | 0.83 | HTR7 (0.38) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL8410568 | 0.82 | HSD17B10 (0.38) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL8411972 | 0.81 | DRD2 (0.43) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL8412306 | 0.81 | HTR7 (0.41) | HTR7DRD2KDM4EALDH1A1MAPT | |
| SCHEMBL8411966 | 0.80 | DRD2 (0.47) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL8413390 | 0.80 | ADRB1 (0.37) | HTR7ALDH1A1 | |
| SCHEMBL8412315 | 0.78 | HTR7 (0.39) | HTR7HTR1ADRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |