Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028579 | 0.76 | GSK3B (0.32) | TNKS2 | |
| SCHEMBL4874802 | 0.68 | CYP1A2 (0.30) | — | |
| Water SCHEMBL11632248 | 0.67 | — | — | |
| SCHEMBL7360794 | 0.67 | — | — | |
| SCHEMBL30642415 | 0.64 | — | — | |
| SCHEMBL422668 | 0.63 | TNKS2 (0.34) | TNKS2 | |
| SCHEMBL6010814 | 0.61 | GDA (0.32) | — | |
| SCHEMBL15386158 | 0.61 | ALDH1A1 (0.35) | — | |
| SCHEMBL8009060 | 0.60 | — | — | |
| SCHEMBL3500581 | 0.60 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122038251-A | Preparation method and application of microorganism for producing 1-phenethyl isoquinoline | 中国科学院分子植物科学卓越创新中心 | 2026-05-15 | — | — | CN | claimed |
| US-12319948-B2 | Pterin-dependent biocatalysts and uses thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2025-06-03 | — | — | US | claimed |
| CN-119925601-A | Application of tetrahydrobiopterin pathway as target in anti-QDPR deletion type tumor | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2025-05-06 | — | — | CN | claimed |
| CN-119736177-A | Yeast engineering strain for synthesizing melatonin and construction method and application thereof | 河南牧业经济学院 | 2025-04-01 | — | — | CN | claimed |
| CN-116042500-B | Recombinant bacterium for producing L-tyrosine and construction method and application thereof | 杭州唯铂莱生物科技有限公司 | 2025-03-25 | — | — | CN | claimed |
| US-20250082692-A1 | ENGINEERED MICROORGANISM FOR TREATING HYPERPHENYLALANINEMIA AND USE THEREOF | COMMBIO THERAPEUTICS CO., LTD. (CN) | 2025-03-13 | — | — | US | claimed |
| CN-119570825-A | Method for efficiently synthesizing protoberberine compounds and application thereof | 中国科学院分子植物科学卓越创新中心 | 2025-03-07 | — | — | CN | claimed |
| CN-119432697-A | Genetically engineered bacterium, construction method thereof and application thereof in production of 5-hydroxytryptophan | 南京腾蔷生物科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| EP-4446407-A1 | ENGINEERED MICROORGANISM FOR TREATING HYPERPHENYLALANINEMIA AND USE THEREOF | Commbio Therapeutics Co., Ltd. (CN) | 2024-10-16 | — | — | EP | claimed |
| CN-113637017-B | Compound containing dihydropterin structure, its preparation method and application | 中国药科大学 | 2024-03-26 | — | — | CN | claimed |
| CN-116042500-A | Recombinant bacterium for producing L-tyrosine and construction method and application thereof | 杭州唯铂莱生物科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-113549588-B | Genetically engineered bacterium for producing 5-hydroxytryptophan and construction method and application thereof | 天津科技大学 | 2023-02-03 | — | — | CN | claimed |
| CN-114272335-A | Traditional Chinese medicine formula for regulating and controlling intestinal function of children | 华子昂 | 2022-04-05 | — | — | CN | claimed |
| CN-114262681-A | Berberine producing strain, and establishing method and application thereof | 中国科学院分子植物科学卓越创新中心 | 2022-04-01 | — | — | CN | claimed |
| US-20220090154-A1 | PTERIN-DEPENDENT BIOCATALYSTS AND USES THEREOF | GEORGIA TECH RESEARCH CORPORATION | 2022-03-24 | — | — | US | claimed |
| CN-106535633-B | Composition containing lipochitooligosaccharides and microorganisms for enhancing plant growth | 诺维信生物农业公司 | 2020-11-17 | — | — | CN | claimed |
| US-20110207753-A1 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2011-08-25 | — | — | US | claimed |
| EP-1696877-A2 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2006-09-06 | — | — | EP | claimed |
| US-20050197341-A1 | Methods for treating pain | GENERAL HOSPITAL CORPORATION, THE | 2005-09-08 | — | — | US | claimed |
| WO-2005048926-A2 | METHODS FOR TREATING PAIN | THE GENERAL HOSPITAL CORPORATION (US) | 2005-06-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250082692-A1 | ENGINEERED MICROORGANISM FOR TREATING HYPERPHENYLALANINEMIA AND USE THEREOF | PAH, ALDH7A1, DDC | TNKS2 4440/4885 |
| US-20110207753-A1 | METHODS FOR TREATING PAIN | SPR, QDPR, SHMT1 | TNKS2 2675/4885 |
| US-20050197341-A1 | Methods for treating pain | SPR, QDPR, SHMT1 | TNKS2 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.