Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239761 | 1.00 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL4059880 | 1.00 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL4062252 | 1.00 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL4067401 | 1.00 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL14380155 | 1.00 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL840549 | 1.00 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| SCHEMBL4058133 | 1.00 | TSHR (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL4258623 | 0.98 | GNAI3 (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Bromide SCHEMBL359338 | 0.98 | TSHR (0.35) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL3245280 | 0.98 | GNAI3 (0.36) | TSHRTHRBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143254-B2 | Methods for modulating ion channels | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20090005386-A1 | Methods for Modulating Ion Channels | PACE UNIVERSITY | 2009-01-01 | — | — | US | disclosed |
| US-7285286-B2 | Antimicrobial surfaces | LONG ISLAND UNIVERSITY (US) | 2007-10-23 | — | — | US | disclosed |
| US-7285286-B2 | Antimicrobial surfaces | LONG ISLAND UNIVERSITY (US) | 2007-10-23 | — | — | US | disclosed |
| US-7241453-B2 | Antimicrobial surfaces | LONG ISLAND UNIVERSITY (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241453-B2 | Antimicrobial surfaces | LONG ISLAND UNIVERSITY (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060199758-A1 | ANTIMICROBIAL SURFACES | ENGEL ROBERT | 2006-09-07 | — | — | US | disclosed |
| US-20050181006-A1 | Antimicrobial surfaces | PACE UNIVERSITY | 2005-08-18 | — | — | US | disclosed |
| EP-1496823-A2 | ANTIMICROBIAL SURFACES | Research Foundation of the City University of New York (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003086477-A2 | ANTIMICROBIAL SURFACES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199758-A1 | ANTIMICROBIAL SURFACES | TLR2, NR0B2, FPR2 | TSHR 87/4885THRB 123/4885GNAI3 4050/4885 |
| US-20050181006-A1 | Antimicrobial surfaces | QSOX1, LBR, FPR1 | TSHR 1704/4885THRB 1878/4885GNAI3 3460/4885 |
| US-20090005386-A1 | Methods for Modulating Ion Channels | KCNJ5, KCNN4, TRPV1 | TSHR 1003/4885THRB 1225/4885GNAI3 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.