Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 6/20 | 0.37 |
| ▸ | PLAU | P00749 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | PLAT | P00750 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | KLK8 | O60259 | 1/20 | 0.33 |
| ▸ | KLK2 | P20151 | 1/20 | 0.33 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433224 | 0.81 | ESR1 (0.58) | CYP3A4TSHRANPEPESR1ESR2 | |
| SCHEMBL28384249 | 0.81 | ATM (0.46) | ANPEPESR1ESR2MAPK1MIF | |
| SCHEMBL31474258 | 0.80 | NOS2 (0.48) | TSHRANPEPESR1ESR2MAPK1 | |
| SCHEMBL11925791 | 0.80 | NLRP3 (0.47) | CYP3A4ANPEPESR1ESR2MAPK1 | |
| SCHEMBL12321430 | 0.80 | CTSC (0.49) | ANPEPESR1ESR2MAPK1KMT2A | |
| SCHEMBL10523997 | 0.79 | ANPEP (0.57) | ANPEPMEN1KMT2A | |
| SCHEMBL11924843 | 0.79 | MIF (0.46) | CYP3A4TSHRANPEPESR1ESR2 | |
| SCHEMBL9788997 | 0.78 | TAS1R3 (0.46) | ANPEPESR1ESR2MAPK1 | |
| SCHEMBL21763387 | 0.77 | ANPEP (0.52) | CYP3A4ANPEPCYP1A2 | |
| SCHEMBL10536462 | 0.77 | ALDH1A1 (0.47) | TSHRANPEPESR1ESR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |