SCHEMBL8417337

SCHEMBL8417337

CCOC(=O)CCCCC(C)=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
ALDH1A1 P00352 4/20 0.50
GAA P10253 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALOX15 P16050 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
DGKA P23743 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
NR1I2 O75469 1/20 0.48
PGR P06401 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
PTGS2 P35354 1/20 0.48
PDE4D Q08499 1/20 0.48
CYP4F2 P78329 1/20 0.47
CYP4A11 Q02928 1/20 0.47
TRPA1 O75762 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6623769 0.98 CYP1A2 (0.59) CYP1A2ALDH1A1GAAHSD17B10ALOX15
SCHEMBL28663838 0.98 CYP1A2 (0.59) CYP1A2ALDH1A1GAAHSD17B10ALOX15
SCHEMBL16022550 0.98 CYP1A2 (0.59) CYP1A2ALDH1A1GAAHSD17B10ALOX15
SCHEMBL6823809 0.98 CYP1A2 (0.59) CYP1A2ALDH1A1GAAHSD17B10ALOX15
SCHEMBL10534701 0.98 CYP1A2 (0.59) CYP1A2ALDH1A1GAAHSD17B10ALOX15
SCHEMBL723390 0.95 CYP1A2 (0.61) CYP1A2ALDH1A1GAAHSD17B10ALOX15
Ethylene SCHEMBL11466234 0.94 CYP1A2 (0.55) CYP1A2ALDH1A1GAAHSD17B10ALOX15
Ethane SCHEMBL11195854 0.93 CYP1A2 (0.59) CYP1A2ALDH1A1GAAHSD17B10ALOX15
2-Nonanone SCHEMBL28983324 0.92 DGKA (0.64) CYP1A2ALDH1A1DGKATSHRLMNA
SCHEMBL8570508 0.90 CYP1A2 (0.73) CYP1A2ALDH1A1GAAHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12390463-B2 Dosage forms and regimens for amino acid compounds PLIANT THERAPEUTICS, INC. (US) 2025-08-19 US disclosed
US-20250223288-A1 AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. 2025-07-10 US disclosed
CN-120091811-A Integrin inhibitors and their use in combination with other agents 普利安特治疗公司 2025-06-03 CN disclosed
EP-4551204-A2 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS Pliant Therapeutics, Inc. (US) 2025-05-14 EP disclosed
EP-4525866-A1 STABILIZATION OF INTEGRIN INHIBITORS Pliant Therapeutics, Inc. (US) 2025-03-26 EP disclosed
EP-4520329-A2 TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS Pliant Therapeutics, Inc. (US) 2025-03-12 EP disclosed
EP-4509512-A2 AMINO ACID COMPOUNDS AND METHODS OF USE Pliant Therapeutics, Inc. (US) 2025-02-19 EP disclosed
CN-118401521-A Integrin inhibitors and their use in combination with other agents 普利安特治疗公司 2024-07-26 CN disclosed
US-20240140888-A1 COMPOSITION COMPRISING AN ALKANE AND AN OXOESTER BIOSYNTHIS (FR) 2024-05-02 US disclosed
US-20240122930-A1 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS PLIANT THERAPEUTICS, INC. 2024-04-18 US disclosed
US-20110027882-A1 Methods and Compositions for Treating Neurological Disease UNIVERSITY OF MASSACHUSETTS 2011-02-03 US disclosed
US-20080221070-A1 METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION 2008-09-11 US disclosed
US-20070093465-A1 Cephem compound DSM IP ASSETS B.V. (NL) 2007-04-26 US disclosed
US-5925680-A Synthetic excitatory amino acids ELI LILLY AND COMPANY (US) 1999-07-20 US disclosed
US-5925782-A Synthetic excitatory amino acids ELI LILLY AND COMPANY (US) 1999-07-20 US disclosed
US-5750566-A NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS ELI LILLY AND COMPANY (US) 1998-05-12 US disclosed
US-4769482-A Cyano and thiocyano intermediates ELI LILLY AND COMPANY (US) 1988-09-06 US disclosed
EP-0108592-B1 LEUKOTRIENE ANTAGONISTS ELI LILLY AND COMPANY (US) 1987-09-30 EP disclosed
US-4661505-A 4-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY) ALKANOIC ACIDS, TETRAZOLES, AND DERIVATIVES ELI LILLY AND COMPANY (US) 1987-04-28 US disclosed
EP-0108592-A1 Leukotriene antagonists ELI LILLY AND COMPANY (US) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240140888-A1 COMPOSITION COMPRISING AN ALKANE AND AN OXOESTER ALKBH2, ABHD12, FAAH2 CYP1A2 163/4885ALDH1A1 938/4885GAA 4071/4885
US-20080221070-A1 METHODS AND COMPOUNDS FOR THE TARGETED DELIVERY OF AGENTS TO BONE FOR INTERACTION THEREWITH SHBG, ESRRA, ESRRG CYP1A2 2384/4885ALDH1A1 2993/4885GAA 2717/4885
US-12390463-B2 Dosage forms and regimens for amino acid compounds ITGB6, ITGA6, ITGAV CYP1A2 3905/4885ALDH1A1 3476/4885GAA 4698/4885
US-20240122930-A1 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS ITGB6, ITGA6, ITGAV CYP1A2 3904/4885ALDH1A1 1094/4885GAA 4360/4885
US-20070093465-A1 Cephem compound HCCS, PCCA, CPS1 CYP1A2 190/4885ALDH1A1 685/4885GAA 2893/4885
US-20250223288-A1 AMINO ACID COMPOUNDS AND METHODS OF USE ITGB6, ITGA6, ITGA5 CYP1A2 4533/4885ALDH1A1 3834/4885GAA 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.