Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.63 |
| ▸ | FABP3 | P05413 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15664279 | 0.85 | POLB (0.49) | HNF4AALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL8102370 | 0.85 | BCAT2 (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL7407371 | 0.83 | HNF4A (0.73) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL5538559 | 0.81 | ALDH1A1 (0.55) | HNF4AALDH1A1MAPTL3MBTL1LMNA | |
| Benzene SCHEMBL28480917 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL133057 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL26624744 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| Benzene SCHEMBL1403559 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL12546288 | 0.80 | SLC6A3 (0.55) | HNF4AALDH1A1MAPTLMNAALOX15 | |
| SCHEMBL2443197 | 0.80 | ALDH1A1 (0.60) | HNF4AALDH1A1MAPTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592033-A | Synthetic method of promacta key intermediate | HANGZHOU HEZE PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-05-06 | — | — | CN | claimed |
| WO-2023112893-A1 | RESIST COMPOSITION AND RESIST PATTERN FORMATION METHOD | 東京応化工業株式会社 | 2023-06-22 | — | — | WO | disclosed |
| CN-104592033-A | Synthetic method of promacta key intermediate | HANGZHOU HEZE PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-05-06 | — | — | CN | disclosed |
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |