SCHEMBL842023

SCHEMBL842023

C[Si](C)([N][Si](C)(C)c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
TP53 P04637 1/20 0.35
NR1H2 P55055 2/20 0.34
NR1H3 Q13133 2/20 0.34
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.32
ALDH1A1 P00352 2/20 0.32
NOS3 P29474 2/20 0.31
NOS1 P29475 2/20 0.31
NOS2 P35228 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL842861 0.77 ESR1 (0.42) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL13380154 0.73 ESR1 (0.44) ESR1ESR2TP53NR1H2NR1H3
SCHEMBL18108202 0.73 ESR1 (0.44) ESR1ESR2TP53NR1H2NR1H3
SCHEMBL7665890 0.73 ESR1 (0.44) ESR1ESR2TP53NR1H2NR1H3
SCHEMBL8967403 0.73 ESR1 (0.44) ESR1ESR2TP53NR1H2NR1H3
SCHEMBL10838037 0.73 ESR1 (0.44) ESR1ESR2TP53NR1H2NR1H3
SCHEMBL10667324 0.72 ESR1 (0.35) ESR1ESR2MAPT
SCHEMBL2169977 0.71 ESR1 (0.48) ESR1ESR2TP53NR1H2NR1H3
SCHEMBL439492 0.71 ESR1 (0.48) ESR1ESR2TP53NR1H2NR1H3
SCHEMBL63526 0.71 ESR1 (0.70) ESR1ESR2TP53NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442045-B1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR BATTERY MODULE AND SENSOR PROVIDED WITH SAME SUMITOMO CHEMICAL CO (JP) 2022-01-12 EP disclosed
US-11063219-B2 Organic photoelectric conversion element, and solar cell module and sensor provided with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-07-13 US disclosed
US-10290809-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-05-14 US disclosed
US-20190115540-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL MODULE AND SENSOR PROVIDED WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-18 US disclosed
EP-3442045-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR BATTERY MODULE AND SENSOR PROVIDED WITH SAME Sumitomo Chemical Company, Limited (JP) 2019-02-13 EP disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
EP-2767553-B1 POLYMER COMPOUND AND ELECTRONIC ELEMENT SUMITOMO CHEMICAL CO (JP) 2017-03-15 EP disclosed
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-9472763-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-10-18 US disclosed
US-8142908-B2 Polymer light-emitting material comprising a conjugated polymer and compound exhibiting light emission from the triplet excited state and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-27 US disclosed
US-8012603-B2 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-06 US disclosed
US-7842941-B2 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-30 US disclosed
US-20100256396-A1 AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-07 US disclosed
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070063190-A1 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070020479-A1 Luminescent-polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE CYBA, BCAT1, CRY1 ESR1 843/4885ESR2 2107/4885TP53 4832/4885
US-10290809-B2 Macromolecular compound EXOSC4, TRPC6, MRPS22 ESR1 1200/4885ESR2 1642/4885TP53 4214/4885
US-20100256396-A1 AROMATIC COMPOUND AHR, AR, NR0B1 ESR1 391/4885ESR2 239/4885TP53 2588/4885
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 ESR1 1141/4885ESR2 903/4885TP53 2438/4885
US-20070063190-A1 Aromatic compound AHR, AR, NR0B1 ESR1 439/4885ESR2 241/4885TP53 2684/4885
US-20160372675-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 ESR1 1200/4885ESR2 1642/4885TP53 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.