Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422211 | 0.87 | ALDH1A1 (0.38) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL8528385 | 0.82 | THRA (0.36) | LMNAKMT2ATACR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8526941 | 0.74 | PPID (0.39) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8423454 | 0.70 | LMNA (0.40) | CTSLCTSBCTSKLMNAKMT2A | |
| SCHEMBL1428501 | 0.68 | TSHR (0.48) | LMNASLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL7201873 | 0.66 | RAPGEF4 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2780510 | 0.66 | ALDH1A1 (0.42) | TACR1ALDH1A1 | |
| SCHEMBL8978333 | 0.65 | ALDH1A1 (0.44) | CTSLCTSBCTSSCTSKLMNA | |
| SCHEMBL11506421 | 0.62 | JAK2 (0.38) | LMNAKMT2AMEN1 | |
| SCHEMBL1401141 | 0.62 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874472-A | Aminoacid derivatives as no synthase inhibitors | GLAXO WELLCOME INC. (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0705257-B1 | AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS | WELLCOME FOUND (GB) | 1998-03-11 | — | — | EP | disclosed |