Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 5/20 | 0.45 |
| ▸ | MEP1A | Q16819 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759713 | 0.87 | MEP1B (0.51) | MEP1BMEP1APTPN1 | |
| SCHEMBL13742232 | 0.85 | HSD11B1 (0.49) | MAOAMAOBHSD11B1THRATHRB | |
| SCHEMBL20633454 | 0.82 | MAOA (0.42) | MAOAMAOBHSD11B1CYP19A1THRA | |
| SCHEMBL10534847 | 0.80 | HSD11B1 (0.45) | MAOAMAOBHSD11B1MEP1BMEP1A | |
| SCHEMBL8421332 | 0.80 | OPRK1 (0.56) | MEP1BMEP1A | |
| SCHEMBL16366240 | 0.79 | GYS1 (0.39) | MAOAMAOBHSD11B1CYP19A1THRA | |
| SCHEMBL14325933 | 0.79 | TAS2R14 (0.49) | MEP1BMEP1A | |
| SCHEMBL19407153 | 0.79 | CYP2C19 (0.47) | MEP1BMEP1APTPN1 | |
| SCHEMBL17494838 | 0.79 | MAOA (0.48) | MAOAMAOBHSD11B1CYP19A1THRA | |
| SCHEMBL212272 | 0.78 | AKR1B1 (0.52) | MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668854-B1 | USE OF N-ARYLMETHYLENE, ETHYLENEDIAMINETRIACETATES N-ARYLMETHYLENE IMINODIACETATES OR N,N'-DIARYLMETHYLENE ETHYLENEDIAMINACETATES FOR USE IN COMBATTING OXIDATIVE STRESS | OREAL (FR) | 1999-10-13 | — | — | EP | claimed |
| US-5703095-A | PREVENTION FERRITIN FROM RELEASING OXYGEN | L'OREAL (FR) | 1997-12-30 | — | — | US | claimed |
| WO-1989006980-A1 | RADIOPHARMACEUTICALS | UNIVERSITY OF QUEENSLAND (AU) | 1989-08-10 | — | — | WO | disclosed |