Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423589 | 0.90 | DRD4 (0.41) | DRD4HPGDALDH1A1L3MBTL1LMNA | |
| SCHEMBL8425466 | 0.90 | DRD4 (0.46) | DRD4HPGDALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL8426096 | 0.81 | MMP1 (0.38) | TMEM97SIGMAR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL8424173 | 0.80 | ALDH1A1 (0.36) | DRD4HPGDALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL8423725 | 0.79 | HSD17B10 (0.34) | DRD4HPGDALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL8424027 | 0.79 | ALDH1A1 (0.36) | DRD4HPGDALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL696193 | 0.71 | HPGD (0.43) | HPGDALDH1A1L3MBTL1 | |
| SCHEMBL8424066 | 0.66 | HPGD (0.43) | DRD4HPGDALDH1A1L3MBTL1CTSK | |
| SCHEMBL28596203 | 0.66 | HPGD (0.57) | HPGDALDH1A1L3MBTL1LMNA | |
| SCHEMBL8425470 | 0.65 | MEN1 (0.42) | HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |