Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425765 | 0.91 | RAB9A (0.40) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL8428131 | 0.90 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL8428211 | 0.89 | NPC1 (0.39) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL8424264 | 0.86 | GABRA2 (0.35) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL8424239 | 0.83 | CNR2 (0.44) | NPC1NPSR1 | |
| SCHEMBL8427939 | 0.82 | CNR1 (0.38) | NPC1RAB9AMAPTRXRAGRIN1 | |
| SCHEMBL8424571 | 0.81 | CNR1 (0.38) | NPC1RAB9ALMNARXRAGRIN1 | |
| SCHEMBL2844850 | 0.78 | NPSR1 (0.40) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL2844847 | 0.78 | NPSR1 (0.40) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL8423316 | 0.78 | USP2 (0.34) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636616-B1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-10-27 | — | — | EP | disclosed |
| EP-0636616-A1 | Process for production of fluoroalkanecarboxamide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-01 | — | — | EP | disclosed |