SCHEMBL8430147

SCHEMBL8430147

CC(C)O[SiH](CCc1ccccc1)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.37
ATM Q13315 1/20 0.37
KMT2A Q03164 2/20 0.35
SIGMAR1 Q99720 5/20 0.35
TSHR P16473 1/20 0.35
TRPA1 O75762 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.34
AOC3 Q16853 1/20 0.34
MAOA P21397 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1313798 0.82 TRPA1 (0.37) TAAR1SIGMAR1TSHRTRPA1MAOA
SCHEMBL705468 0.71 SIGMAR1 (0.42) KMT2ASIGMAR1L3MBTL1
SCHEMBL16813954 0.70 TAAR1 (0.37) TAAR1KMT2ASIGMAR1TSHRAOC3
SCHEMBL703613 0.70 SIGMAR1 (0.44) KMT2ASIGMAR1L3MBTL1MAOA
SCHEMBL14841098 0.69 SIGMAR1 (0.35) TAAR1ATMSIGMAR1TRPA1AOC3
SCHEMBL1325408 0.67 MAOA (0.43) TAAR1ATMSIGMAR1AOC3MAOA
SCHEMBL706759 0.67 ALDH1A1 (0.38) TAAR1ATMAOC3SLC6A2SLC6A3
SCHEMBL704978 0.66 TSHR (0.41) TAAR1SIGMAR1TSHRTRPA1MAOA
SCHEMBL14841792 0.66 SIGMAR1 (0.38) TAAR1ATMSIGMAR1AOC3MAOA
SCHEMBL1313829 0.64 SLC6A2 (0.39) TAAR1TSHRTRPA1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6007927-A FOR PREVENTING UNDESIRABLE DETERIORATION OF DIELECTRIC PROPERTIES AND SHORTENING OF DURABILITY INDUCED BY THE IMPURITY IONS PRESENT IN POWDERY BARIUM TITANATE SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1999-12-28 US disclosed
US-5777038-A FLUOROPOLYMER; ELECTROLUMINESCENCE SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1998-07-07 US disclosed