Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435310 | 0.90 | CHRNB2 (0.61) | CHRNA3CHRNB2CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL8437928 | 0.90 | CHRNB2 (0.61) | CHRNA3CHRNB2CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL6588716 | 0.84 | CHRNA3 (0.59) | CHRNA3CHRNB2CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL7472876 | 0.84 | CHRNA3 (0.59) | CHRNA3CHRNB2CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL8434692 | 0.83 | CHRNB2 (0.52) | CHEK2CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL6608981 | 0.82 | HCRTR1 (0.69) | CHEK2HCRTR1ALOX5APHCRTR2GPR119 | |
| SCHEMBL6613800 | 0.81 | CHEK2 (0.52) | CHEK2CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL6615093 | 0.81 | HCRTR1 (0.58) | CHEK2HCRTR1HRH2HRH1ALOX5AP | |
| SCHEMBL7449606 | 0.81 | CHEK2 (0.57) | CHEK2HCRTR1HRH2HRH1ALOX5AP | |
| SCHEMBL6609250 | 0.80 | CHEK2 (0.56) | CHEK2HCRTR1HRH2HRH1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948793-A | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release | ABBOTT LABORATORIES (US) | 1999-09-07 | — | — | US | disclosed |