Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443199 | 0.81 | TDP1 (0.43) | — | |
| SCHEMBL8441858 | 0.80 | CYP2D6 (0.44) | — | |
| SCHEMBL8438243 | 0.79 | CHRNB4 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL8672721 | 0.76 | PTGS2 (0.40) | — | |
| SCHEMBL8668966 | 0.76 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL8439867 | 0.76 | LMNA (0.44) | — | |
| SCHEMBL8442148 | 0.76 | KMT2A (0.44) | — | |
| SCHEMBL8441415 | 0.75 | LMNA (0.43) | — | |
| SCHEMBL8551375 | 0.75 | KDM4E (0.39) | — | |
| SCHEMBL8522389 | 0.74 | POLB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |