Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441415 | 0.95 | LMNA (0.43) | LMNASMN1; SMN2PIK3CBPIK3CDPIK3R1 | |
| SCHEMBL8443199 | 0.90 | TDP1 (0.43) | SMN1; SMN2PDE2APOLB | |
| SCHEMBL8441858 | 0.86 | CYP2D6 (0.44) | POLBMET | |
| SCHEMBL8672721 | 0.82 | PTGS2 (0.40) | LMNASMN1; SMN2POLB | |
| SCHEMBL8442148 | 0.81 | KMT2A (0.44) | MKNK1POLBPIK3CD | |
| SCHEMBL8551375 | 0.80 | KDM4E (0.39) | LMNASMN1; SMN2POLB | |
| SCHEMBL8439870 | 0.78 | LMNA (0.47) | LMNAMKNK1SMN1; SMN2PDE2AOXTR | |
| SCHEMBL8668966 | 0.78 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2 | |
| SCHEMBL8552372 | 0.77 | PTGS2 (0.36) | LMNASMN1; SMN2POLB | |
| SCHEMBL8438242 | 0.76 | CHRNB4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |