Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443199 | 0.84 | TDP1 (0.43) | POLBMAPTTSHR | |
| SCHEMBL8441858 | 0.81 | CYP2D6 (0.44) | POLBMAPTKCNH2 | |
| SCHEMBL8439867 | 0.81 | LMNA (0.44) | MKNK1POLBPIK3CD | |
| SCHEMBL8522389 | 0.80 | POLB (0.44) | KMT2AMEN1POLBMAPTKCNH2 | |
| SCHEMBL8672721 | 0.80 | PTGS2 (0.40) | KMT2AMEN1POLBMAPTTSHR | |
| SCHEMBL8442151 | 0.79 | MEN1 (0.44) | KMT2AMEN1MKNK1MKNK2POLB | |
| SCHEMBL8441415 | 0.78 | LMNA (0.43) | KCNH2PIK3CDTSHR | |
| SCHEMBL8551375 | 0.78 | KDM4E (0.39) | KMT2AMEN1POLBMAPTTSHR | |
| SCHEMBL8438242 | 0.76 | CHRNB4 (0.44) | — | |
| SCHEMBL8668966 | 0.76 | SMN1; SMN2 (0.38) | KMT2AMAPTKCNH2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |