Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442525 | 0.88 | TBXA2R (0.52) | ALDH1A1LMNASMN1; SMN2TBXA2R | |
| SCHEMBL8442976 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GAATBXA2RMEN1KMT2A | |
| SCHEMBL8441478 | 0.85 | ALDH1A1 (0.48) | ALDH1A1GAATBXA2RMEN1KMT2A | |
| SCHEMBL8440583 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAGAASMN1; SMN2TBXA2R | |
| SCHEMBL8437957 | 0.85 | MEN1 (0.54) | ALDH1A1LMNAGAATBXA2RMEN1 | |
| SCHEMBL8440900 | 0.84 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBTBXA2RMEN1 | |
| SCHEMBL8443153 | 0.82 | MEP1B (0.47) | ALDH1A1LMNASMN1; SMN2TBXA2R | |
| SCHEMBL8438766 | 0.82 | LMNA (0.53) | ALDH1A1LMNASMN1; SMN2SLC1A3SLC1A2 | |
| SCHEMBL8439050 | 0.81 | VCAM1 (0.54) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8521716 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAGAASMN1; SMN2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |