Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8070683 | 0.99 | ALDH1A1 (0.52) | ALDH1A1MAPK1GFERSMN1; SMN2KMT2A | |
| SCHEMBL8068849 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPK1GFERSMN1; SMN2KMT2A | |
| SCHEMBL8444240 | 0.82 | MRGPRX1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL8444776 | 0.82 | SIGMAR1 (0.46) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1USP2 | |
| Hydrochloric Acid SCHEMBL8070680 | 0.82 | MRGPRX1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL8068683 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL8068487 | 0.81 | SIGMAR1 (0.45) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1USP2 | |
| SCHEMBL8446348 | 0.81 | CA2 (0.43) | ALDH1A1KMT2ATSHRCA9 | |
| Hydrochloric Acid SCHEMBL8059609 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNATSHR | |
| SCHEMBL8446065 | 0.81 | CYP19A1 (0.50) | ALDH1A1SMN1; SMN2KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |