Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446573 | 0.83 | FFAR1 (0.56) | FFAR1SLC7A11GAA | |
| SCHEMBL7868880 | 0.82 | FFAR1 (0.47) | FFAR1POLBGRM5ALDH1A1RAB9A | |
| SCHEMBL8448556 | 0.80 | MEP1B (0.52) | ALDH1A1RAB9AKDM4ENPC1GAA | |
| SCHEMBL7675914 | 0.77 | LMNA (0.65) | RAB9AKDM4ENPC1GAAHPGD | |
| SCHEMBL28588397 | 0.77 | ALDH1A1 (0.51) | POLBALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL5892649 | 0.74 | MMP2 (0.67) | POLB | |
| SCHEMBL5090951 | 0.72 | CA1 (0.57) | ALDH1A1RAB9AKDM4ENPC1GAA | |
| SCHEMBL19450297 | 0.72 | MMP2 (0.56) | POLBALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL6799380 | 0.72 | ALDH1A1 (0.56) | ALDH1A1RAB9AKDM4ENPC1GAA | |
| SCHEMBL6806640 | 0.72 | MMP13 (0.51) | ALDH1A1RAB9AKDM4ENPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |