SCHEMBL8457900

SCHEMBL8457900

C#Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
CA4 P22748 1/20 0.61
LMNA P02545 1/20 0.52
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.50
NT5E P21589 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.45
CYP2C9 P11712 5/20 0.45
POLB P06746 1/20 0.42
CYP2D6 P10635 1/20 0.42
PTPN1 P18031 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HDAC8 Q9BY41 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16564195 0.98 CA12 (0.59) CA12CA1CA2CA9CA14
SCHEMBL28958523 0.90 TSHR (0.69) CA12CA1CA2CA9CA14
SCHEMBL8930972 0.82 ALDH1A1 (0.58) CA12CA1CA2CA9CA14
SCHEMBL15326125 0.82 TSHR (0.58) CA12CA1CA2CA9CA14
SCHEMBL28958513 0.81 TSHR (0.57) CA12CA1CA2CA9CA14
SCHEMBL3843538 0.80 CA12 (0.67) CA12CA1CA2CA9CA14
SCHEMBL150334 0.79 LMNA (0.77) CA12CA1CA2CA9CA14
SCHEMBL4840191 0.78 LMNA (0.54) CA12CA1CA2CA9CA14
SCHEMBL253713 0.76 CA12 (0.61) CA12CA1CA2CA9CA14
SCHEMBL6019009 0.76 CA2 (1.00) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717737-B1 CHELANTS AS CONTRAST ENHANCING AGENTS NYCOMED SALUTAR INC (US) 1999-04-07 EP claimed
CN-117334976-A Sulfonated benzene polyphenyl ionomer-based high-temperature moisturizing enhanced composite proton exchange membrane and preparation method thereof 河南大学 2024-01-02 CN disclosed
CN-117276608-A Enhanced sulfonated benzene polyphenyl proton exchange membrane and preparation method thereof 河南大学 2023-12-22 CN disclosed
CN-117276609-A Hydrogen bond organic framework doped sulfonated benzene polyphenyl ionomer type proton exchange membrane and preparation method thereof 河南大学 2023-12-22 CN disclosed
WO-2023189803-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
WO-2023189799-A1 SELF CROSS-LINKABLE POLYMER AND RESIST UNDERLAYER FILM-FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
CN-115589736-A Perovskite composite layer and solar cell 嘉庚创新实验室 2023-01-10 CN disclosed
US-20220214355-A1 SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-07-07 US disclosed
CN-113853372-A Thio-heterocyclic exchange chemistry and uses thereof 弗吉尼亚大学专利基金委员会 2021-12-28 CN disclosed
EP-3924348-A2 SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF University of Virginia Patent Foundation (US) 2021-12-22 EP disclosed
WO-2020214336-A9 SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2020-11-19 WO disclosed
WO-2020214336-A2 SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2020-10-22 WO disclosed
CN-104428667-B Agent for separating optical isomers 国立大学法人名古屋大学 2017-06-09 CN disclosed
US-8642626-B2 Ethinyl-pyrazole derivative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2014-02-04 US disclosed
EP-2599775-A1 ETHINYL-PYRAZOLE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2013-06-05 EP disclosed
US-20130123500-A1 ETHINYL-PYRAZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD (JP) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220214355-A1 SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF TST, TPST2, SRMS CA12 3992/4885CA1 3215/4885CA2 3500/4885
US-20130123500-A1 ETHINYL-PYRAZOLE DERIVATIVE GABRE, GRIN3A, GRIK5 CA12 4440/4885CA1 2027/4885CA2 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.